Selected Publication:
Guenes, T.
The Role of Neurofilament Light Chain (NfL) as a Biomarker in Parkinson ‘s Disease
Humanmedizin; [ Diplomarbeit ] Medizinische Universität Graz; 2025. pp. 118
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- Authors Med Uni Graz:
- Advisor:
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Kern Daniela
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Schwingenschuh Petra
- Altmetrics:
- Abstract:
- This study aimed to assess the relationship between serum neurofilament light chain (NfL) levels and clinical markers of disease severity, as well as their diagnostic and prognostic value in patients with Parkinson's disease (PD) compared to healthy controls (HC). In addition, a systematic literature review was conducted to provide an overview of the current evidence on NfL levels in PD. Data from the Prospective Registry on Movement Disorders (PROMOVE, 2010, Graz), was used to support and compare with the findings from the systematic literature review.