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Selected Publication:
Taumberger, N.
Preemptive local analgesia at vaginal hysterectomy: a systematic review
Doktoratsstudium der Medizinischen Wissenschaft; Humanmedizin; [ Dissertation ] Medizinische Universität Graz; 2022. pp. 99
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FullText
- Authors Med Uni Graz:
- Taumberger Nadja
- Advisor:
- Simonis Holger
- Tamussino Karl
- Trutnovsky Gerda
- Altmetrics:
- Abstract:
- Background: Hysterectomy for benign indications is one of the most common operations in women. Vaginal hysterectomy is the recommended approach if feasible and guidelines and ERAS protocols recommend multimodal analgesia. Objectives: This was a systematic review of the effectiveness of local preemptive analgesia for postoperative pain control in women undergoing vaginal hysterectomy. Search Strategy: MEDLINE, EMBASE, the Cochrane Central Register of Controlled Trials and the Cochrane Database of Systematic Reviews were searched systematically to identify eligible studies published through September 25th, 2019. Selection criteria: Randomized controlled trials and systematic reviews addressing local preemptive analgesia in comparison to placebo at vaginal hysterectomy. Data Collection and Analysis: Data were extracted by two independent reviewers. Results were compared and disagreement was resolved by discussion between the reviewers. Forty-seven studies met inclusion criteria for full-text review. Four RCTs, including a total of 197 patients, and 2 SRs were included in the review. Main results: We found significant decreases in postoperative pain scores up to 6 hours and postoperative opioid requirements in the first 24 h after surgery in patients receiving preemptive local analgesia. Conclusion: Preemptive local analgesia at vaginal hysterectomy results in less pain and less postoperative opioid consumption.