Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Lindner, W; Rath, M; Stoschitzky, K; Semmelrock, HJ.
Pharmacokinetic data of propranolol enantiomers in a comparative human study with (S)- and (R,S)-propranolol.
Chirality. 1989; 1(1):10-13
Doi: 10.1002/chir.530010105
Web of Science
PubMed
FullText
FullText_MUG
Google Scholar
- Co-Autor*innen der Med Uni Graz
- Semmelrock Hans-Jürgen
- Stoschitzky Kurt
- Altmetrics:
- Dimensions Citations:
- Plum Analytics:
- Scite (citation analytics):
- Abstract:
- The pharmacokinetics of (S)-propranolol were compared after the oral administration of a 40 mg dose of the pure enantiomer and an 80 mg dose of a racemic mixture of (R,S)-propranolol. The results of this study indicate that the bioavailability of (S)-propranolol, as expressed by the mean area under the concentration-time curve (AUC) and maximum serum concentration, is lower after 40 mg of the optically pure drug than after the racemic drug.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Biological Availability -
- Female -
- Half-Life -
- Humans -
- Male -
- Propranolol - pharmacokinetics
- Stereoisomerism - pharmacokinetics