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SHR Neuro Cancer Cardio Lipid Metab Microb

Ahammer, H; Helige, C; Dohr, G; Weiss-Fuchs, U; Juch, H.
Fractal dimension of the choriocarcinoma cell invasion front
PHYSICA D. 2008; 237(4): 446-453. Doi: 10.1016/j.physd.2007.09.016
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Leading authors Med Uni Graz
Ahammer Helmut
Co-authors Med Uni Graz
Dohr Gottfried
Helige Christine
Juch Herbert
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Abstract:
The Minkowski dimension was calculated for the determination of the invasiveness of cancer cells, which were brought in close contact (confronted) to host tissues and cultivated in vitro. The confrontation cultures were histologically sectioned and stained immunohistochemically. Digital images of these sections were segmented, processed and the specimens' boundaries were investigated. The invasion front was treated as a fractal. The value of the Minkowski dimension increased with increased invasiveness of the cells. The Minkowski dimension could be used as a quantitative measure for cancer diagnosis. (c) 2007 Elsevier B.V. All rights reserved.

Find related publications in this database (Keywords)
Fractal dimension
invasion front
cancer
choriocarcinoma
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