Medizinische Universität Graz - Research portal
Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Gellner, V; Kurschel, S; Scarpatetti, M; Mokry, M.
Lymphocytic hypophysitis in the pediatric population.
Childs Nerv Syst. 2008; 24(7): 785-792.
Doi: 10.1007/s00381-007-0577-1
(- Case Report)
Web of Science
PubMed
FullText
FullText_MUG
- Leading authors Med Uni Graz
- Gellner Verena
- Kurschel-Lackner Senta
- Co-authors Med Uni Graz
- Mokry Michael
- Scarpatetti Michael
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- Abstract:
- BACKGROUND: Lymphocytic hypophysitis (LYH) is a rare inflammatory disease of the pituitary gland that usually affects women in their ante- or immediate postpartum period; males are affected less frequently than females. An autoimmune pathogenesis is suggested. Symptoms comprise anterior and/or posterior pituitary insufficiency of varying degrees. So far, specific characteristics of this rare disease in childhood are not well described. CASE HISTORY: We report the case of a 12-year-and-11-month-old boy with histologically confirmed LYH clinically presenting with diabetes insipidus. A high-dose steroid therapy was administered, in which the therapeutic effect was uncertain. His 6-year follow-up is presented. DISCUSSION: The literature is reviewed for children presenting with LYH; their characteristics, pituitary involvement, and clinical follow-up are listed and discussed. CONCLUSION: Even though magnetic resonance imaging can be highly suspicious for LYH, only surgical exploration can confirm the diagnosis. The efficacy of medical treatment is still controversial; a close follow-up is necessary to control and correct the endocrinological function, if required.
- Find related publications in this database (using NLM MeSH Indexing)
- Child -
- Diabetes Insipidus - complications
- Follow-Up Studies -
- Humans -
- Lymphocytosis - complications
- Magnetic Resonance Imaging -
- Male -
- Pediatrics -
- Pituitary Diseases - complications
- Find related publications in this database (Keywords)
- lymphocytic hypophysitis
- lymphocytic infundibulo-hypophysitis
- diabetes insipidus
- pediatric