Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Mayer, N; Lembeck, F; Goedert, M; Otten, U.
Effects of antibodies against nerve growth factor on the postnatal development of substance P-containing sensory neurons.
NEUROSCI LETT. 1982; 29(1): 47-52.
Doi: 10.1016/0304-3940(82)90362-7
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- Co-Autor*innen der Med Uni Graz
- Lembeck Fred
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- Abstract:
- Administration of anti-nerve growth factor (NGF)-antibodies to newborn rats produces a marked but reversible reduction of the substance P content in dorsal root ganglia. This is in contrast to the effect of anti-NGF-antibodies on sympathetic ganglia, where they cause a destruction of the adrenergic neurons as is evident in the irreversible reduction of tyrosine hydroxylase activity.
- Find related publications in this database (using NLM MeSH Indexing)
- Animals -
- Animals, Newborn - growth and development
- Antibodies - immunology
- Ganglia, Spinal - analysis
- Nerve Growth Factors - immunology
- Neurons, Afferent - immunology
- Rats - immunology
- Rats, Inbred Strains - immunology
- Spinal Cord - analysis
- Substance P - analysis
- Time Factors - analysis