Medizinische Universität Graz - Research portal
Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Metzler, H; Huber, K; Kozek-Langenecker, S; Vicenzi, MN; Münch, A.
Coronary stents, dual antiplatelet therapy and peri-operative problems
ANAESTHESIST. 2007; 56(4): 401-410.
Doi: 10.1007/s00101-007-1171-3
Web of Science
PubMed
FullText
FullText_MUG
- Leading authors Med Uni Graz
- Metzler Helfried
- Co-authors Med Uni Graz
- Vicenzi Martin
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- Abstract:
- Up to 90% of all percutaneous coronary interventions include coronary artery stenting. Dual antiplatelet therapy, usually involving acetylsalicyl acid combined with clopidogrel, is mandatory for patients with coronary artery stents. The duration of antiplatelet therapy for bare metal stents is 3-4 weeks, for drug eluting stents 6-12 months. Preoperative discontinuation of both drugs increases the risk of stent thrombosis, continuation the risk of relevant bleeding. According to the recommendations of anaesthesiological and cardiological societies, perioperative management has to balance the risk of bleeding vs stent thrombosis. Surgery involving a high risk of bleeding can require the discontinuance of both substances. In cases of high thrombosis risk, at least the acetylsalicyl acid should be continued until the day of surgery. For patients under antiplatelet therapy scheduled for local anaesthesia, national recommendations exist. A close collaboration between the anaesthesiologist, cardiologist and surgeon is essential for appropriate pre-, intra- and postoperative management.
- Find related publications in this database (using NLM MeSH Indexing)
- Angioplasty, Transluminal, Percutaneous Coronary -
- Aspirin - administration and dosage Aspirin - therapeutic use
- Humans -
- Perioperative Care -
- Platelet Aggregation Inhibitors - administration and dosage Platelet Aggregation Inhibitors - therapeutic use
- Platelet Function Tests -
- Stents -
- Thrombosis - etiology
- Ticlopidine - administration and dosage Ticlopidine - analogs and derivatives Ticlopidine - therapeutic use
- Find related publications in this database (Keywords)
- percutaneous coronary intervention
- coronary stent implantation
- dual antiplatelet drug therapy
- perioperative stent thrombosis
- regional anaesthesia