Medizinische Universität Graz - Research portal
Selected Publication:
Kessler, HH; Dohr, G; Desoye, G; Winter, R.
Expression of histocompatibility antigens in human pre-implantation embryos
Arch Gynecol Obstet. 1989; 245(1-4): 161-162.
Doi: 10.1007/BF02417223
PubMed
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- Co-authors Med Uni Graz
- Desoye Gernot
- Dohr Gottfried
- Winter Raimund
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- Abstract:
- The expression of HLA antigens on polyploid human preimplantation embryos, obtained in an in vitro fertilization program, was investigated by indirect immunofluorescence test using a panel of well-defined monoclonal antibodies. Neither HLA class I antigens and beta 2-microglobulin, nor HLA class II molecules could be detected on blastomeres and the zona pellucida. It is supposed that the absence of HLA antigens on human preimplantation embryos may be one of the mechanisms important for the acceptance of the embryo by the immunocompetent mother.
- Find related publications in this database (using NLM MeSH Indexing)
- Embryo - immunology
- Embryo Transfer - immunology
- Fertilization in Vitro - immunology
- Gene Expression - immunology
- HLA Antigens - genetics
- Humans - genetics
- Immune Tolerance - genetics