Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Schalamon, J; Lindahl, H; Saarikoski, H; Rintala, RJ.
Endoscopic follow-up in esophageal atresia-for how long is it necessary?
J Pediatr Surg. 2003; 38(5):702-704
Doi: 10.1016/jpsu.2003.50187
Web of Science
PubMed
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- Führende Autor*innen der Med Uni Graz
- Schalamon Johannes
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- Abstract:
- Purpose: The aim of this study was to find out how long it is necessary to follow-up esophageal atresia patients endoscopically to prevent irreversible mucosal changes. Methods: Seventy-four of 79 long-term survivors with esophageal atresia and primary anastomosis underwent a total of 322 esophagogastroduodenoscopies during a follow-up period of 0.5 to 19 years (mean, 10.3) after the primary operation. For analysis, the biopsy findings were divided into 2 groups: good, histologically normal or only mildly inflamed mucosa; unfavorable, moderate or severe esophagitis or gastric metaplasia. Fundoplication irrespective of indications was considered unfavorable. The results were analyzed using actuarial survival analysis; the changing point was when a "good" turned into "unfavorable." Results: Forty-five patients (61%) remained in the "good" group throughout the study period; 15 of those (20%) had completely normal findings. Nine patients (12%) had moderate, one (1%) had severe esophagitis, and 13 patients (18%) had gastric metaplasia. Fundoplication was performed on 21 patients (28%). Conclusions: About 40% of esophageal atresia patients eventually have significant esophageal mucosal pathology or need to have a fundoplication. The majority of these changes appear before the age of 3 years. Routine endoscopic follow-up of esophageal atresia patients is recommended at least to the age of 3 years.
- Find related publications in this database (using NLM MeSH Indexing)
- Anastomosis, Surgical -
- Endoscopy -
- Esophageal Atresia - mortality
- Esophagitis - diagnosis
- Follow-Up Studies -
- Humans -
- Infant, Newborn -
- Metaplasia - diagnosis
- Retrospective Studies -
- Risk -
- Stomach - pathology
- Survival Analysis -
- Survivors -
- Time Factors -
- Tracheoesophageal Fistula - surgery
- Find related publications in this database (Keywords)
- esophageal atresia
- long-term follow-up
- endoscopy