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Selected Publication:
Fink-Puches, R; Hofmann-Wellenhof, R; Smolle, J; Kerl, H.
Confocal laser scanning microscopy: a new optical microscopic technique for applications in pathology and dermatology.
J Cutan Pathol. 1995; 22(3):252-259
Doi: 10.1111/j.1600-0560.1995.tb00747.x
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- Leading authors Med Uni Graz
- Fink-Puches Regina
- Co-authors Med Uni Graz
- Hofmann-Wellenhof Rainer
- Kerl Helmut
- Smolle Josef
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- Abstract:
- Confocal laser scanning microscopy (CLSM) is a new optical microscopic technique, which offers significant advantages over conventional microscopy. CLSM is microscopy of optical sections. Light, which is emitted from regions other than the focal plane, is cut off by introducing a diaphragm in the beam path. The result is an optical "slice", which shows more details because the blurring from out of focus haze disappears. It has been repeatedly used in experimental, but also in diagnostic dermatopathology. The "in vivo" confocal microscopy, applied directly to the intact skin provides details of living cells in the superficial layers comparable to that of fixed and stained tissue. While the extent of its future applications is hard to predict, its potential for applications in dermatology appears enormous, particularly for studies of fixed or living tissues, where it is desirable to obtain clear images many micrometers below the surface of the tissue under examination.
- Find related publications in this database (using NLM MeSH Indexing)
- Animals -
- Dermatology - methods
- Humans - methods
- Microscopy, Confocal - methods
- Pathology, Clinical - methods