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Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Resch, B; Jammernegg, A; Perl, E; Riccabona, M; Maurer, U; Müller, WD.
Correlation of grading and duration of periventricular echodensities with neurodevelopmental outcome in preterm infants.
Pediatr Radiol. 2006; 36(8):810-815
Doi: 10.1007/s00247-006-0178-2
Web of Science
PubMed
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- Leading authors Med Uni Graz
- Resch Bernhard
- Co-authors Med Uni Graz
- Maurer-Fellbaum Ute
- Müller Wilhelm
- Riccabona Michael
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- Abstract:
- Background: Transient periventricular echodensities (PVE) in preterm infants affect neurodevelopmental outcome. Objective: To correlate the duration and grading of PVE with neurodevelopmental outcome. Materials and methods: A retrospective, single-centre cohort study of infants with PVE diagnosed by ultrasonography from 1995 to 2000 with blinded grading and recognition of duration of PVE. Results: A total of 72 infants (median gestational age 32 weeks, median birth weight 1,668 g) were diagnosed as having PVE. Minor neurological abnormalities were diagnosed in seven (10%), cerebral palsy in six (8%), developmental delay in seven (10%), and mild mental retardation in two (3%) of the infants. Differences regarding adverse outcome were not significant between infants with severity grade 1 compared to severity grade 2 (16% and 22%, respectively). There was a significant increase in adverse neurodevelopmental outcome with increasing duration of PVE. Of 33 infants with duration of PVE < 7 days, 1 (3%) had an adverse neurodevelopmental outcome, compared to 6 (24%) of 25 infants with a duration of PVE of 7-14 days, and 6 (43%) of 14 infants with a duration of PVE > 14 days (P < 0.002, RR 7.920, 95% CI 1.017-61.661; P < 0.001, RR 14.143, 95% CI 1.871-106.895, respectively). Conclusion: The duration, but not the grading, of transient PVE was significantly correlated with neurodevelopmental outcome.
- Find related publications in this database (using NLM MeSH Indexing)
- Cerebral Palsy - etiology Cerebral Palsy - ultrasonography
- Cerebral Ventricles - abnormalities Cerebral Ventricles - ultrasonography
- Cohort Studies -
- Developmental Disabilities - etiology Developmental Disabilities - ultrasonography
- Echoencephalography -
- Female -
- Humans -
- Infant, Newborn -
- Infant, Premature -
- Infant, Premature, Diseases - ultrasonography
- Intellectual Disability - etiology Intellectual Disability - ultrasonography
- Leukomalacia, Periventricular - complications Leukomalacia, Periventricular - ultrasonography
- Male -
- Pregnancy -
- Prognosis -
- Retrospective Studies -
- Find related publications in this database (Keywords)
- brain
- periventricular echodensities
- preterm
- infants