Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Mangge, H; Vojinovic, J; Schauenstein, K.
Do chemokines spark autoimmunity in juvenile and adult rheumatic disease?
Immunobiology. 2002; 206(4):459-471
Doi: 10.1078/0171-2985-00194
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PubMed
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- Führende Autor*innen der Med Uni Graz
- Mangge Harald
- Co-Autor*innen der Med Uni Graz
- Schauenstein Konrad
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- Abstract:
- The recent increase in knowledge on chemokines contributes substantially to the understanding of autoimmune inflammatory diseases, as cell migration is an essential prerequisite for the local immune reaction. The purpose of this review is to summarize the essential functions of chemokines in immune activation and to examine their role(s) in the initiation and perpetuation of autoimmunity in juvenile idiopathic arthritis and adult rheumatic disease. The possible relevance of chemokines as therapeutical targets will be discussed.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Arthritis, Juvenile Rheumatoid - etiology Arthritis, Juvenile Rheumatoid - immunology
- Arthritis, Rheumatoid - etiology Arthritis, Rheumatoid - immunology
- Autoimmunity -
- Chemokines - immunology
- Child -
- Humans -
- Models, Immunological -
- Receptors, Chemokine - immunology