Medizinische Universität Graz - Research portal
Selected Publication:
Maier, A; Tomaselli, F; Sankin, O; Anegg, U; Fell, B; Renner, H; Pinter, H; Friehs, GB; Smolle-Jüttner, FM.
Acid-related diseases following retrosternal stomach interposition.
Hepatogastroenterology. 2001; 48(39):899-902
Web of Science
PubMed
Google Scholar
- Leading authors Med Uni Graz
- Maier Alfred
- Co-authors Med Uni Graz
- Anegg Udo
- Fell Birgit
- Pinter Hans
- Renner Heiko
- Sankin Oliver
- Smolle-Juettner Freyja-Maria
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- Abstract:
- BACKGROUND/AIMS: Esophagectomy and reconstruction with retrosternal stomach interposition implies bilateral truncal vagotomy, which supposedly causes gastric functional impairment. METHODOLOGY: Esophagectomy and reconstruction with retrosternal stomach interposition was performed on 15 men (mean age: 58.4 years) and 3 women (mean age: 43.6 years). The stomach was pedicled on the right gastric and right gastroepiploic artery without performing pyloroplasty. The cervical side-to-end anastomosis was sutured manually. The functional results were assessed 2-4 years postoperatively, by determining 24-hour qualitative intragastric pH-measurement, fluoroscopical gastric emptying studies, fasting gastrin levels, and endoscopy with biopsy studies. RESULTS: Endoscopy and biopsy confirmed esophagitis in 12 patients, gastritis in 15 and a gastric ulcer in 1 case. Fluoroscopic examination documented a normal passage of contrast medium in 17, slight impairment in 1 case treated by balloon dilatation of the pylorus. Qualitative intragastric pH-measurement revealed a total pH < 3 in 22.5-98.05% of measuring events (mean: 74.31%) within 24 hours, in 18 cases. Only 4 patients had pH < 3 in less than 50%. Fasting gastrin levels (normal range: 25-110 mU/L) varied from 48.78 mU/L-168.20 (mean: 85.23 mU/L). Only 3 patients had levels > 110 mU/L (maximum: 168.20 mU/L). CONCLUSIONS: Acid-related diseases may also occur after truncal vagotomy and retrosternal stomach interposition. Routine follow-up endoscopy and biopsy studies should be done to prevent inflammatory complications and maintain the patient's quality of life.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Aged -
- Anastomosis, Surgical -
- Esophagectomy - methods
- Female -
- Gastric Acidity Determination -
- Gastric Emptying - physiology
- Gastrins - blood
- Gastritis - diagnosis
- Humans -
- Male -
- Middle Aged -
- Postoperative Complications - diagnosis
- Stomach - surgery
- Stomach Ulcer - diagnosis
- Vagotomy, Truncal -
- Find related publications in this database (Keywords)
- truncal vagotomy
- acid-related diseases