Medizinische Universität Graz - Research portal
Selected Publication:
Schnedl, WJ; Liebminger, A; Roller, RE; Lipp, RW; Krejs, GJ.
Hemoglobin variants and determination of glycated hemoglobin (HbA1c).
Diabetes Metab Res Rev. 2001; 17(2):94-98
Doi: 10.1002/dmrr.186
[Poster]
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- Leading authors Med Uni Graz
- Schnedl Wolfgang
- Co-authors Med Uni Graz
- Krejs Günter Josef
- Lipp Rainer
- Roller-Wirnsberger Regina
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- Abstract:
- Measurement of glycated hemoglobin in diabetic patients is an established procedure for evaluating long-term control of diabetes. The Diabetes Control and Complications Trial (DCCT), as well as the United Kingdom Prospective Diabetes Study (UKPDS), confirmed the direct relationship between the degree of glycemic control as estimated by glycohemoglobin (GHb) determinations and the development and progression of long-term complications in diabetic patients. Samples with known interferences of HbA(1c) determination as hemoglobinopathies are specifically excluded from certification testing and there are no guidelines or requirements for comparability of samples containing hemoglobin (Hb) variants. This paper reviews the interference of Hb variants on determination methods of glycated hemoglobin as they result in false HbA(1c) results.
- Find related publications in this database (using NLM MeSH Indexing)
- Biomarkers - blood
- Blood Glucose - metabolism
- Genetic Variation -
- Glycated Hemoglobin A - analysis
- Hemoglobins - genetics
- Hemoglobins, Abnormal - analysis
- Hemoglobins, Abnormal - genetics
- Humans -
- Find related publications in this database (Keywords)
- hemoglobin variants
- glycated hemoglobin
- HbA(1C)
- determination methods