Medizinische Universität Graz - Research portal
Selected Publication:
Maier, A; Gaggl, A; Klemen, H; Santler, G; Anegg, U; Fell, B; Kärcher, H; Smolle-Jüttner, FM; Friehs, GB.
Review of severe osteoradionecrosis treated by surgery alone or surgery with postoperative hyperbaric oxygenation.
Br J Oral Maxillofac Surg. 2000; 38(3):173-176
Doi: 10.1054/bjom.1999.0285
Web of Science
PubMed
FullText
FullText_MUG
Google Scholar
- Leading authors Med Uni Graz
- Maier Alfred
- Co-authors Med Uni Graz
- Anegg Udo
- Fell Birgit
- Kärcher Hans
- Klemen Huberta
- Santler Gert
- Smolle-Juettner Freyja-Maria
- Altmetrics:
- Dimensions Citations:
- Plum Analytics:
- Scite (citation analytics):
- Abstract:
- We reviewed 41 patients with osteoradionecrosis of the mandible. Each patient was treated by radical resection followed by external beam irradiation. The diagnosis of infected osteoradionecrosis was confirmed clinically, radiologically, and histologically. After operation had failed, 20/41 were given hyperbaric oxygen (HBO) as in 'salvage' treatment. Daily sessions of HBO 2.5 ATA for 60 minutes (mean: 29 sessions) were given. The other 21 patients were treated by operation and antibiotics alone. HBO group (n = 20): The overall success rate for HBO after operation had failed was 13/20. Repeated debridement as first-line treatment followed by postoperative HBO was successful in 12/19. In seven of 19 patients, partial mandibulectomy and microvascular transplantation were required as second-line treatment, and this was successful in five. Primary partial mandibulectomy and microvascular transplantation followed by HBO was successful in 1 patient. Non-HBO group (n = 21): Repeated debridement was successful in 10/11 patients. Partial mandibulectomy was required as second-line treatment in the remaining one. In the other 10, partial mandibulectomy and microvascular transplantation were successful as first-line treatment in four. In the remaining six, further surgical intervention became necessary and were successful for 5-17 months (mean: 13). With a success rate of 13/20, we do not recommend HBO for the treatment of osteoradionecrosis.
- Find related publications in this database (using NLM MeSH Indexing)
- Aged -
- Bacterial Infections - complications
- Blood Vessels - transplantation
- Cranial Irradiation - adverse effects
- Humans - adverse effects
- Hyperbaric Oxygenation - utilization
- Mandibular Diseases - etiology
- Middle Aged - etiology
- Mouth Neoplasms - radiotherapy
- Oral Surgical Procedures - utilization
- Osteoradionecrosis - complications
- Postoperative Care - complications
- Retrospective Studies - complications
- Salvage Therapy - complications
- Treatment Failure - complications
- Treatment Outcome - complications