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Zenahlik, P; Fink-Puches, R; Kapp, KS; Kerl, H; Cerroni, L.
[Therapy of primary cutaneous B-cell lymphomas].
Hautarzt. 2000; 51(1):19-24 Doi: 10.1007/s001050050005
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Co-authors Med Uni Graz
Cerroni Lorenzo
Fink-Puches Regina
Kapp Karin S.
Kerl Helmut
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Abstract:
Primary cutaneous B-cell lymphomas (PCBCL) represent a unique type of extranodal B-cell lymphomas. Recently, the "European Organization for Research and Treatment of Cancer (EORTC)-Cutaneous Lymphoma Study Group" classified PCBCL into two major groups: one with low-grade malignancy and excellent prognosis (follicle center cell lymphoma, immunocytoma/marginal zone B-cell lymphoma) and the other with intermediate malignancy and worse prognosis (large B-cell lymphoma of the leg). The clinical course and the prognosis of both groups clearly distinguish them from nodal lymphomas with similar morphological aspects, thus underlying the need for different treatment modalities. We investigated retrospectively the therapeutic data from 51 patients with PCBCL (40 low grade lymphomas, 11 large B-cell lymphomas). Several treatment modalities were used: total excision, radiotherapy, polychemotherapy, systemic corticosteroids, systemic antibiotics, as well as a variety of combination treatments. Recurrence, dissemination and/or death of the patients were not significantly related to any single treatment modality. In our opinion, the choice of treatment for PCBCL depends on the histologic classification, the number, spread and localization of the infiltrates, and on the general condition of the patient.
Find related publications in this database (using NLM MeSH Indexing)
Adult -
Aged -
Aged, 80 and over -
Combined Modality Therapy -
Female -
Humans -
Lymphoma, B-Cell - diagnosis
Lymphoma, B-Cell - pathology
Lymphoma, B-Cell - therapy
Male -
Middle Aged -
Skin - pathology
Skin Neoplasms - diagnosis
Skin Neoplasms - pathology
Skin Neoplasms - therapy
Treatment Outcome -

Find related publications in this database (Keywords)
cutaneous B-cell lymphomas
therapy
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