Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Feigl, B; Sill, H; Haas, A.
Serous detection of the neuroretina in Waldenström disease. A case report
Klin Monatsbl Augenheilkd. 1999; 215(1):64-67
Doi: 10.1055/s-2008-1034672
(- Case Report)
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- Führende Autor*innen der Med Uni Graz
- Feigl Beatrix
- Co-Autor*innen der Med Uni Graz
- Haas Anton
- Sill Heinz
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- Abstract:
- BACKGROUND: Waldenstrom's Macroglobulinemia is a monoclonal gammopathy producing pathologic IgM antibodies with increased blood viscosity, platelet dysfunction and retinal hemorrhages. As a complication a serous detachment of the macula is described. The pathogenesis of the serous detachment is still not fully understood. CASE REPORT: A 73-year-old male patient was presented with Waldenstrom's Macroglobulinemia, a typical hyperviscosity retinopathy and serous detachment of the macula. We performed fluorescein (FA)- and indocyaningreenangiography (ICG) before and three months after chemotherapy. Especially ICG-angiographic findings revealed a serous detachment that was restricted to the posterior pole but showed a fingershaped enlargement to the optic disc. CONCLUSION: FA- and especially ICG-angiographic findings can help to get more information about the pathogenetic mechanism of serous detachment in Waldenstrom's Macroglobulinemia. Besides toxic alteration of the retinal pigmentepithelium, oncotic and hydrostatic pressure, a pathologic communication between the optic disc, the subarachnoid space and the subretinal space is discussed.
- Find related publications in this database (using NLM MeSH Indexing)
- Aged -
- Blood Viscosity -
- Coloring Agents - diagnostic use
- Fluorescein Angiography - diagnostic use
- Humans - diagnostic use
- Indocyanine Green - diagnostic use
- Male - diagnostic use
- Retinal Detachment - diagnosis
- Sensitivity and Specificity - diagnosis
- Waldenstrom Macroglobulinemia - diagnosis
- Find related publications in this database (Keywords)
- Waldenstroms Macroglobulinemia
- Serous Detachment of the Retina Indocyaningreenangiography