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SHR Neuro Cancer Cardio Lipid Metab Microb

Bauer, B; Mayrhofer, M; Zarfl, M; Kamolz, LP; Luze, H; Nischwitz, SP.
A 10-year recurrence-free natural course of high-risk stage II cutaneous melanoma: A case report.
JPRAS Open. 2026; 48: 205-212. Doi: 10.1016/j.jpra.2025.11.029 (- Case Report) [OPEN ACCESS]
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Leading authors Med Uni Graz
Bauer Benedikt
Co-authors Med Uni Graz
Kamolz Lars-Peter
Luze Hanna
Mayrhofer Marcel
Nischwitz Sebastian
Zarfl Maximilian
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Abstract:
BACKGROUND: pT4b melanoma of the skin, especially the nodular subtype with present ulceration, typically entails a poor prognosis with high risk for metastatic spread. The accuracy of classic risk prediction models lacks at times. When situated in the face, these malignancies can pose a specific challenge to reconstructive surgeons. Profound fears of cancer treatment further complicate the management of these cases. CASE PRESENTATION: We present a case of facial reconstruction in a 58-year-old female patient with a high-risk stage II melanoma with recurrence-free survival (RFS) despite an almost 10-year delay of surgical treatment due to existential fears. CONCLUSIONS: The presented case provides several key takeaways. First, from a dermatological standpoint, clinicians must expect the unexpected and should look for explanations. Second, from a reconstructive view, complex cases are rarely linear-staged revisions, and setbacks are integral to surgical success. Finally, from a human perspective, sincere empathy, and emotional intelligence are indispensable.

Find related publications in this database (Keywords)
High-risk melanoma
Surgical oncology
Reconstructive surgery
Disease-free survival
Metastasis
Facial reconstruction
Empathy
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