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SHR Neuro Cancer Cardio Lipid Metab Microb

Schlemmer, AJ; Gorkiewicz, G; Uggowitzer, MM; Salamon, S; Jost, P; Talakic, E.
18 F-FDG PET/CT in NUT Carcinoma of the Thorax.
Clin Nucl Med. 2025; 50(11):1062-1063 Doi: 10.1097/RLU.0000000000005872 (- Case Report)
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Leading authors Med Uni Graz
Schlemmer Anselm Johannes
Talakic Emina
Co-authors Med Uni Graz
Gorkiewicz Gregor
Jost Philipp
Salamon Spela
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Abstract:
NUT carcinoma (NUTc) is a rare, aggressive cancer characterized by rearrangement of the NUTM1 gene on chromosome 15q14. We present the case of a 32-year-old man with a persisting cough, reduced general condition, and B symptoms for 2 months. CT imaging revealed a highly suspicious mass in the right lung, infiltrating hilar structures, and the mediastinum. Staging with 18 F-FDG PET/CT demonstrated pathologic 18 F-FDG uptake within the tumor. Histology, immunohistochemistry, and molecular analysis confirmed NUTc of the lung. Metabolic imaging modalities may play a key role in staging, restaging, and assessing treatment response in patients with NUTc.
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Humans - administration & dosage
Male - administration & dosage
Fluorodeoxyglucose F18 - administration & dosage
Adult - administration & dosage
Positron Emission Tomography Computed Tomography - administration & dosage
Thoracic Neoplasms - diagnostic imaging
Carcinoma - diagnostic imaging
Neoplasm Proteins - administration & dosage
Nuclear Proteins - administration & dosage

Find related publications in this database (Keywords)
F-18-FDG PET/CT
PET/CT
NUT carcinoma
thorax
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