Medizinische Universität Graz - Research portal
Selected Publication:
Smolle, KH; Hofmann, G; Kaufmann, P; Lueger, A; Brunner, G.
Q.E.D. Alcohol test: a simple and quick method to detect ethanol in saliva of patients in emergency departments. Comparison with the conventional determination in blood.
Intensive Care Med. 1999; 25(5):492-495
Doi: 10.1007%2Fs001340050886
Web of Science
PubMed
FullText
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- Leading authors Med Uni Graz
- Smolle Karl-Heinz
- Co-authors Med Uni Graz
- Brunner Gernot
- Hofmann Guenter
- Lueger Andreas
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- Abstract:
- OBJECTIVE: The aim of this pilot study was to assess whether ethanol concentrations in saliva are comparable to those in blood and to evaluate whether this new non-invasive saliva alcohol test is suitable for use in emergency departments. DESIGN: Prospective, open, non-randomised study. SETTING: University hospital emergency department. PATIENTS AND METHODS: 100 consecutive patients who were admitted to the emergency department whose smell and/or behaviour indicated alcohol abuse. Fifteen patients participated as a control group after they were asked to abstain from alcohol consumption for 24 h before the study. INTERVENTIONS: Blood and saliva samples were obtained at the same time for ethanol measurement. The Q.E.D. Alcohol Test A350 was used in order to measure the concentration of ethanol in saliva. Blood samples were analysed by the alcohol dehydrogenase method. RESULTS: The mean difference between the ethanol levels in blood and saliva was -0.1 mg/dl, whereas the values measured in saliva were on average 0.1 mg/dl higher than those measured in blood (p = 0.002). CONCLUSION: The Q.E.D. Alcohol Test A 350, which uses saliva, is well suited for quantitative determination of alcohol levels. The levels measured in saliva correlate well with those measured in blood at both the lower and the upper end of the scale. Because this test is quick and easy to perform by emergency room personnel and the results are accurate enough for clinical purposes, it should prove valuable to determine whether impaired consciousness is related to alcohol intoxication or to other likely causes.
- Find related publications in this database (using NLM MeSH Indexing)
- Adolescent -
- Adult -
- Alcoholic Intoxication - blood
- Emergency Service, Hospital - blood
- Ethanol - blood
- Female - blood
- Humans - blood
- Male - blood
- Middle Aged - blood
- Pilot Projects - blood
- Prospective Studies - blood
- Reagent Kits, Diagnostic - blood
- Saliva - chemistry
- Sensitivity and Specificity - chemistry
- Statistics, Nonparametric - chemistry
- Substance Abuse Detection - methods
- Find related publications in this database (Keywords)
- Saliva Ethanol Test
- Blood Ethanol Test
- Alcohol Abuse Intoxication
- Emergency Room