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SHR Neuro Cancer Cardio Lipid Metab Microb

Bracic, M; Nagy, BM; Plohl, O; Lackner, F; Steindorfer, T; Fischer, RC; Heinze, T; Olschewski, A; Kleinschek, KS; Nagaraj, C; Mohan, T.
Antithrombogenic polysaccharide coatings to improve hemocompatibility, protein-repellence, and endothelial cell response
ISCIENCE. 2024; 27(9): 110692 Doi: 10.1016/j.isci.2024.110692 [OPEN ACCESS]
Web of Science PubMed PUBMED Central FullText FullText_MUG

 

Leading authors Med Uni Graz
Chandran Nagaraj
Co-authors Med Uni Graz
Nagy Miklos Bence
Olschewski Andrea
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Abstract:
Polyester biomaterials play a crucial in vascular surgery, but suffer from unspecific protein adsorption, sues, we investigated the functionalization of polyester biomaterials with antithrombogenic polysaccharide coatings. A two-step and water-based method was used to coat cationized polycaprolactone with icantly increased the anticoagulant activity and reduced the thrombogenicity of polycaprolactone, particcorrelated with the type and sulfate content of the coatings.

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