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SHR Neuro Cancer Cardio Lipid Metab Microb
Flucher, C; Windhaber, J; Gasparella, P; Castellani, C; Tschauner, S; Mittl, B; Wolfschluckner, V; Singer, G; Till, H.
Long-term motor activity, cardiopulmonary performance and quality of life in abdominal wall defect patients.
Pediatr Res. 2024; 95(4):1101-1109
Doi: 10.1038/s41390-023-02900-y
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- Leading authors Med Uni Graz
- Flucher Christina
- Singer Georg
- Co-authors Med Uni Graz
- Castellani Christoph
- Gasparella Paolo
- Mittl Barbara
- Till Holger
- Tschauner Sebastian
- Windhaber Jana Maria
- Wolfschluckner Vanessa
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- Abstract:
- AIM: To assess whether patients born with an abdominal wall defect (AWD) have impaired cardiorespiratory performance capacity, motor skills, core stability or quality of life in a long-term follow up. METHODS: Patients diagnosed with AWD between 2002 and 2013 were invited to participate in the study, which included clinical examination, spirometry, cardiopulmonary exercise performance testing, assessment of motor activity, ultrasound, electromyography of the abdominal wall and assessment of the Gastrointestinal Quality of Life Index (GIQLI). The results were compared to a healthy control group matched for age, sex, BMI, and physical activity levels. RESULTS: In total, 18 AWD patients (mean age 12.6 ± 3.5 years) were included and there were no significant differences in anthopometric data compared to the control group (n = 18). AWD patients had a significantly lower GIQLI score (AWD mean 137.2 ± 6.8 vs. control mean 141.4 ± 4.9; p = 0.038) and were affected by decreased motor abilities with significantly higher Dordel-Koch-Test values (AWD median 3.54/IQR 1 vs. control median 2.8/IQR 1; p = 0.005). CONCLUSION: Follow-up examinations of AWD patients revealed decreased motor abilities and GIQLI scores while cardiopulmonary function was not different compared to healthy controls. The clinical impact of these findings remains to be elucidated. IMPACT: Clinical examination, assessment of the gastrointestinal quality of life, sport medical testing, electromyography and abdominal wall ultrasound were performed in patients with congenital abdominal wall defect and compared to an age and sex matched healthy control group. Results of spirometry and spiroergometry, ultrasound or electromyography did not significantly differ between the groups. Significantly decreased locomotor function and gastrointestinal quality of life were found in patients with abdominal wall defect. However, the clinical impact of these findings remains to be elucidated.
- Find related publications in this database (using NLM MeSH Indexing)
- Humans - administration & dosage
- Child - administration & dosage
- Adolescent - administration & dosage
- Abdominal Wall - abnormalities
- Quality of Life - administration & dosage
- Exercise Test - administration & dosage
- Gastrointestinal Tract - administration & dosage
- Motor Activity - administration & dosage