Medizinische Universität Graz - Research portal

Go directly to the nagivation.
Go directly to the content.

Navigation/Search

Selected Publication:

SHR Neuro Cancer Cardio Lipid Metab Microb

Artzi-Medvedik, R; Kob, R; Di Rosa, M; Lattanzio, F; Corsonello, A; Yehoshua, I; Roller-Wirnsberger, RE; Wirnsberger, GH; Mattace-Raso, FUS; Tap, L; Gil, PG; Formiga, F; Moreno-Gonzalez, R; Kostka, T; Guligowska, A; Arnlov, J; Carlsson, AC; Freiberger, E; Melzer, I.
Quality of Life and Kidney Function in Older Adults: Prospective Data of the SCOPE Study
J CLIN MED. 2023; 12(12): 3959 Doi: 10.3390/jcm12123959 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

Co-authors Med Uni Graz: Roller-Wirnsberger Regina; Wirnsberger Gerhard
Altmetrics:
Dimensions Citations:
Plum Analytics:
Scite (citation analytics):
Abstract:: A longitudinal alteration in health-related quality of life (HRQoL) over a two-year period and its association with early-stage chronic kidney disease (CKD) progression was investigated among 1748 older adults (>75 years). HRQoL was measured by the Euro-Quality of Life Visual Analog Scale (EQ-VAS) at baseline and at one and two years after recruitment. A full comprehensive geriatric assessment was performed, including sociodemographic and clinical characteristics, the Geriatric Depression Scale-Short Form (GDS-SF), Short Physical Performance Battery (SPPB), and estimated glomerular filtration rate (eGFR). The association between EQ-VAS decline and covariates was investigated by multivariable analyses. A total of 41% of the participants showed EQ-VAS decline, and 16.3% showed kidney function decline over the two-year follow-up period. Participants with EQ-VAS decline showed an increase in GDS-SF scores and a greater decline in SPPB scores. The logistic regression analyses showed no contribution of a decrease in kidney function on EQ-VAS decline in the early stages of CKD. However, older adults with a greater GDS-SF score were more likely to present EQ-VAS decline over time, whereas an increase in the SPPB scores was associated with less EQ-VAS decline. This finding should be considered in clinical practice and when HRQoL is used to evaluate health interventions among older adults.
Find related publications in this database (Keywords): quality of life; chronic kidney disease; older adults; prospective studies; cohort studies; disease progression