Medizinische Universität Graz - Research portal
Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Casado, AL; Santonja, C; Garcia-Garcia, M; Olave-Rubio, MT; Lorda-Espes, M; Fink-Puches, R; Cerroni, L; Prieto-Torres, L.
Essential thrombocythemia manifesting as livedoid and purpuric skin lesions: Report of two cases and literature review
J CUTAN PATHOL. 2023;
Doi: 10.1111/cup.14417
Web of Science
PubMed
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- Co-authors Med Uni Graz
- Cerroni Lorenzo
- Fink-Puches Regina
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- Abstract:
- Essential thrombocythemia is a chronic myeloproliferative syndrome which usually runs its course as an asymptomatic elevated platelet count. Cutaneous manifestations secondary to microcirculation abnormalities are rare but can represent a helpful diagnostic clue in order to prevent major thromboembolic events. We report two cases of heterogeneous livedoid and "net-like" skin lesions in the context of essential thrombocythemia with identical histopathologic findings (medium-sized blood vessels with luminal obliteration by eosinophilic material, mostly positive for the platelet marker CD61, without vasculitis). In conclusion, we seek to raise awareness of the clinicopathological features of essential thrombocythemia to allow for prompt diagnosis and treatment.