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Chillon, TS; Demircan, K; Weiss, G; Minich, WB; Schenk, M; Schomburg, L.
Detection of antibodies to SARS-CoV-2 after vaccination in seminal plasma and their association to sperm parameters.
Int J Infect Dis. 2023; 130:161-165
Doi: 10.1016/j.ijid.2023.03.018
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- Co-authors Med Uni Graz
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Schenk Michael
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Weiss Gregor
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- Abstract:
- There is a public concern that COVID-19 vaccination and SARS-CoV-2 antibodies (Abs) negatively affect male fertility. However, the evidence for the presence of SARS-CoV-2 Abs in seminal plasma (SP) is lacking. We examined whether Abs were detectable in SP after COVID-19 vaccination in 86 men using a direct Ab measurement and by quantification of their neutralizing activity. The results show the presence of SARS-CoV-2 Abs in SP, with a strong correlation to the serum Abs, increasing with the number of vaccinations. Furthermore, the Ab titers are correlating with the neutralization activity. The SARS-CoV-2 vaccination parameters showed no association with the markers of sperm quality. In conclusion, this study indicates substantial levels of Abs in SP after COVID-19 vaccination that correlate with serum Ab titers but do not associate with sperm quality.
- Find related publications in this database (Keywords)
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COVID-19
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Fertility
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Men?s health
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Reproduction