Medizinische Universität Graz - Research portal
Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Zajic, P; Eichinger, M; Eichlseder, M; Hallmann, B; Honnef, G; Fellinger, T; Metnitz, B; Posch, M; Rief, M; Metnitz, PGH.
Association of immediate versus delayed extubation of patients admitted to intensive care units postoperatively and outcomes: A retrospective study.
PLoS One. 2023; 18(1): e0280820
Doi: 10.1371/journal.pone.0280820
[OPEN ACCESS]
Web of Science
PubMed
FullText
FullText_MUG
- Leading authors Med Uni Graz
- Zajic Paul
- Co-authors Med Uni Graz
- Eichinger Michael
- Eichlseder Michael
- Hallmann Barbara
- Honnef Gabriel
- Metnitz Philipp
- Rief Martin
- Altmetrics:
- Dimensions Citations:
- Plum Analytics:
- Scite (citation analytics):
- Abstract:
- AIM OF THIS STUDY: This study seeks to investigate, whether extubation of tracheally intubated patients admitted to intensive care units (ICU) postoperatively either immediately at the day of admission (day 1) or delayed at the first postoperative day (day 2) is associated with differences in outcomes. MATERIALS AND METHODS: We performed a retrospective analysis of data from an Austrian ICU registry. Adult patients admitted between January 1st, 2012 and December 31st, 2019 following elective and emergency surgery, who were intubated at the day 1 and were extubated at day 1 or day 2, were included. We performed logistic regression analyses for in-hospital mortality and over-sedation or agitation following extubation. RESULTS: 52 982 patients constituted the main study population. 1 231 (3.3%) patients extubated at day 1 and 958 (5.9%) at day 2 died in hospital, 464 (1.3%) patients extubated at day 1 and 613 (3.8%) at day 2 demonstrated agitation or over-sedation after extubation during ICU stay; OR (95% CI) for in-hospital mortality were OR 1.17 (1.01-1.35, p = 0.031) and OR 2.15 (1.75-2.65, p<0.001) for agitation or over-sedation. CONCLUSIONS: We conclude that immediate extubation as soon as deemed feasible by clinicians is associated with favourable outcomes and may thus be considered preferable in tracheally intubated patients admitted to ICU postoperatively.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult - administration & dosage
- Humans - administration & dosage
- Retrospective Studies - administration & dosage
- Airway Extubation - administration & dosage
- Length of Stay - administration & dosage
- Time Factors - administration & dosage
- Intensive Care Units - administration & dosage