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SHR Neuro Cancer Cardio Lipid Metab Microb

Schary, W; Paskali, F; Rentschler, S; Ruppert, C; Wagner, GE; Steinmetz, I; Deigner, HP; Kohl, M.
Open-Source, Adaptable, All-in-One Smartphone-Based System for Quantitative Analysis of Point-of-Care Diagnostics.
Diagnostics (Basel). 2022; 12(3): Doi: 10.3390/diagnostics12030589 [OPEN ACCESS]
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Co-authors Med Uni Graz: Steinmetz Ivo; Wagner-Lichtenegger Gabriel
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Abstract:: Point-of-care (POC) diagnostics, in particular lateral flow assays (LFA), represent a great opportunity for rapid, precise, low-cost and accessible diagnosis of disease. Especially with the ongoing coronavirus disease 2019 (COVID-19) pandemic, rapid point-of-care tests are becoming everyday tools for identification and prevention. Using smartphones as biosensors can enhance POC devices as portable, low-cost platforms for healthcare and medicine, food and environmental monitoring, improving diagnosis and documentation in remote, low-resource locations. We present an open-source, all-in-one smartphone-based system for quantitative analysis of LFAs. It consists of a 3D-printed photo box, a smartphone for image acquisition, and an R Shiny software package with modular, customizable analysis workflow for image editing, analysis, data extraction, calibration and quantification of the assays. This system is less expensive than commonly used hardware and software, so it could prove very beneficial for diagnostic testing in the context of pandemics, as well as in low-resource countries.
Find related publications in this database (Keywords): point-of-care diagnostics; lateral flow assays; R Shiny application; quantitative image analysis; smartphone-based system