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Taumberger, N; Schütz, AM; Jeitler, K; Siebenhofer, A; Simonis, H; Bornemann-Cimenti, H; Laky, R; Tamussino, K.
Preemptive local analgesia at vaginal hysterectomy: a systematic review.
Int Urogynecol J. 2022; 33(9):2357-2366 Doi: 10.1007/s00192-021-04999-1 [OPEN ACCESS]
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Leading authors Med Uni Graz
Taumberger Nadja
Co-authors Med Uni Graz
Bornemann-Cimenti Helmar
Jeitler Klaus
Laky Rene Walter
Schütz Anna-Maria
Siebenhofer-Kroitzsch Andrea
Simonis Holger
Tamussino Karl
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Abstract:
INTRODUCTION AND HYPOTHESIS: We conducted a systematic review of the effectiveness of local preemptive analgesia for postoperative pain control in women undergoing vaginal hysterectomy. METHODS: MEDLINE, EMBASE, the Cochrane Central Register of Controlled Trials and the Cochrane Database of Systematic Reviews were searched systematically to identify eligible studies published through September 25, 2019. Only randomized controlled trials and systematic reviews addressing local preemptive analgesia compared to placebo at vaginal hysterectomy were considered. Data were extracted by two independent reviewers. Results were compared, and disagreement was resolved by discussion. Forty-seven studies met inclusion criteria for full-text review. Four RCTs, including a total of 197 patients, and two SRs were included in the review. RESULTS: Preemptive local analgesia reduced postoperative pain scores up to 6 h and postoperative opioid requirements in the first 24 h after surgery. CONCLUSION: Preemptive local analgesia at vaginal hysterectomy results in less postoperative pain and less postoperative opioid consumption.
Find related publications in this database (using NLM MeSH Indexing)
Analgesia - methods
Analgesics, Opioid - therapeutic use
Female - administration & dosage
Humans - administration & dosage
Hysterectomy - administration & dosage
Hysterectomy, Vaginal - administration & dosage
Pain, Postoperative - drug therapy, etiology, prevention & control
Systematic Reviews as Topic - administration & dosage

Find related publications in this database (Keywords)
Postoperative pain
Local preemptive analgesia
Vaginal hysterectomy
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