Medizinische Universität Graz - Research portal
Selected Publication:
Aigner, RM; Fueger, GF; Wolf, G.
Parathyroid scintigraphy: first experiences with technetium (III)-99m-Q12.
Eur J Nucl Med. 1997; 24(3):326-329
Doi: 10.1007/s002590050061
Web of Science
PubMed
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- Leading authors Med Uni Graz
- Aigner Reingard
- Co-authors Med Uni Graz
- Wolf Gerhard
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- Abstract:
- We report the preliminary results of a prospective study demonstrating technetium(III)-99m furifosmin (Q12) uptake in histologically proven parathyroid adenomas. Scintigraphy was performed in 12 patients with hyperparathyroidism. Q12 correctly identified the parathyroid adenomas by focal prolonged tracer retention in ten of the 12 patients. In the two patients without localized tracer retention, no parathyroid adenoma could be identified surgically, either. The retention half-times ranged from 0.5 to 1.8 h (mean 1.27) in the parathyroid adenomas and from 0.3 to 1.2 h (mean 1.05) in the thyroid gland. Our preliminary results show that Q12 is a feasible, sensitive tracer for parathyroid scintigraphy. In comparison to sestamibi (MIBI) and tetrofosmin, Q12 displays short retention in the thyroid gland, which would seem rather advantageous. Further evaluation is needed to determine which among Q12, tetrofosmin and MIBI is most sensitive for the detection especially of small parathyroid adenomas, and which tracer properties will best reflect the degree of endocrine activity.
- Find related publications in this database (using NLM MeSH Indexing)
- Adenoma - radionuclide imaging
- Adult -
- Aged -
- Feasibility Studies -
- Female -
- Furans - diagnostic use
- Humans -
- Hyperparathyroidism - radionuclide imaging
- Male -
- Middle Aged -
- Organophosphorus Compounds - diagnostic use
- Organotechnetium Compounds - diagnostic use
- Parathyroid Neoplasms - radionuclide imaging
- Prospective Studies -
- Radiopharmaceuticals - diagnostic use
- Sensitivity and Specificity -
- Technetium Tc 99m Sestamibi - diagnostic use
- Find related publications in this database (Keywords)
- Tc-99m Furifosmin
- Tc-99m Sestamibi
- Tc-99m Tetrofosmin
- Parathyroid Adenoma
- Hyperparathyroidism