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Deinlein, T; Michor, C; Hofmann-Wellenhof, R; Schmid-Zalaudek, K; Fink-Puches, R.
The importance of total-body photography and sequential digital dermatoscopy for monitoring patients at increased melanoma risk.
J Dtsch Dermatol Ges. 2020; 18(7):692-697 Doi: 10.1111/ddg.14158 [OPEN ACCESS]
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Leading authors Med Uni Graz: Fink-Puches Regina; Kränke Teresa Maria
Co-authors Med Uni Graz: Hofmann-Wellenhof Rainer; Michor Carina; Schmid-Zalaudek Karin
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Abstract:: The incidence of melanoma is rising and prevention plays an important role. Multiple nevi as well as a medical history of melanoma are important risk factors. In affected patients, a two-step algorithm consisting of total-body photography (TBP) and sequential digital dermatoscopy (SDD) is a helpful diagnostic tool. This was a retrospective observational study that lasted six years in order to evaluate the significance of the two-step algorithm. Cases were evaluated based on distinct dermoscopic patterns and statistical analyses were performed with the latest version of SPSS. 6020 dermoscopic images of 214 patients were included. TBP was performed at a mean interval of 16.9 months (SD ± 1.43 months), while SDD was performed every 9.9 months (SD ± 1.68 months). The number needed to excise was 4.6 and the number needed to monitor was 548. Excisions were mostly performed because dynamic changes were observed. A total of eleven melanomas were detected and had a mean tumor thickness of 0.44 mm (SD ± 0.15 mm; range 0.2-0.6 mm). Invasive melanomas had a tumor thickness of less than 0.6 mm, thus providing evidence of an effective strategy for early melanoma detection. Excisions of benign nevi were minimized as indicated by a low number needed to excise. © 2020 The Authors. Journal der Deutschen Dermatologischen Gesellschaft published by John Wiley & Sons Ltd on behalf of Deutsche Dermatologische Gesellschaft.
Find related publications in this database (using NLM MeSH Indexing): Algorithms -; Dermoscopy - methods; Humans -; Melanoma - diagnosis; Melanoma - pathology; Photography -; Retrospective Studies -; Skin Neoplasms - diagnosis; Skin Neoplasms - pathology; Time Factors -