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Seibel, A; Zechner, PM; Berghold, A; Holter, M; Braß, P; Michels, G; Leister, N; Gemes, G; Donauer, R; Giebler, RM; Sakka, SG.
B-Lines for the assessment of extravascular lung water: Just focused or semi-quantitative?
Acta Anaesthesiol Scand. 2020; 64(7):953-960 Doi: 10.1111/aas.13586 [OPEN ACCESS]
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Co-authors Med Uni Graz: Berghold Andrea; Gemes Geza; Holter Magdalena; Zechner Peter
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Abstract:: B-lines as typical artefacts of lung ultrasound are considered as surrogate measurement for extravascular lung water. However, B-lines develop in the sub-pleural space and do not allow assessment of the whole lung. Here, we present data from the first observational multi-centre study focusing on the correlation between a B-lines score and extravascular lung water in critically ill patients suffering from a variety of diseases. In 184 adult patients, 443 measurements were obtained. B-lines were counted and expressed in a score which was compared to extravascular lung water, measured by single-indicator transpulmonary thermodilution. Appropriate correlation coefficients were calculated and receiver operating characteristics (ROC-) curves were plotted. Overall, B-lines score was correlated with body weight-indexed extravascular lung water characterized by r = .59. The subgroup analysis revealed a correlation coefficient in patients without an infection of r = .44, in those with a pulmonary infection of r = .75 and in those with an abdominal infection of r = .23, respectively. Using ROC-analysis the sensitivity and specificity of B-lines for detecting an increased extravascular lung water (>10 mL/kg) was 63% and 79%, respectively. In patients with a P/F ratio <200 mm Hg, sensitivity and specificity to predict an increased extravascular lung water was 71% and 93%, respectively. Assessment of B-lines does not accurately reflect actual extravascular lung water. In presence of an impaired oxygenation, B-lines may reliably indicate increased extravascular lung water as cause of the oxygenation disorders. © 2020 The Acta Anaesthesiologica Scandinavica Foundation. Published by John Wiley & Sons Ltd.
Find related publications in this database (Keywords): B-Lines; extravascular lung water; interstitial syndrome; lung edema; oxygenation index; transpulmonary thermodilution