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SHR Neuro Cancer Cardio Lipid Metab Microb
Tomic, J; Metzler, P; Alcon, A; Jakse, N; Zemann, W; Schanbacher, M; Zrnc, TA.
Weight gain in infants with Pierre Robin sequence.
J Craniomaxillofac Surg. 2020; 48(6): 555-559.
Doi: 10.1016/j.jcms.2020.03.009
Web of Science
PubMed
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- Leading authors Med Uni Graz
- Tomic Josip
- Zrnc Tomislav
- Co-authors Med Uni Graz
- Jakse Norbert
- Metzler Philipp
- Schanbacher Monika
- Zemann Wolfgang
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- Abstract:
- To determine weight gain during treatment with the modified palatal plate (MPP) in infants with isolated and syndromic Pierre Robin Sequence (PRS) suffering from micrognathia, upper airway obstruction (UAO), and failure to thrive (FTT), the authors conducted a retrospective study of infants treated with the MPP. The main outcome measure was infant weight (g) for up to three months after birth. Demographic and outcome data (associated syndromes, comorbidities, presence of cleft lip or palate, intubation attempts, tracheotomy and cleft repair) were collected. 14 children born January 2010 - December 2019 were included. The majority (86%) of infants showed highly significant weight gain (p < 0.001) within a 3-month period (mean pretreatment weight 3147 g with a SD of 425 g vs mean weight at three months 4435 g with a SD of 635 g). Syndromic PRS was found in 7% of infants. 43% of nonsyndromic PRS patients were found to have other congenital anomalies. Genetic testing showed normal karyotypes in 93% of infants and a microdeletion in 7% of infants. 21% of infants required tracheotomy, but no patients required mandibular distraction (MDO) or tongue-lip adhesion (TLA) to relieve UAO. PRS infants treated with the MPP showed highly significant weight gain within a 3-month period and did not require mandibular surgery for early airway management, but faster gain of weight might have implications for strategies to perform surgery at an earlier point in time. Copyright © 2020 European Association for Cranio-Maxillo-Facial Surgery. Published by Elsevier Ltd. All rights reserved.
- Find related publications in this database (Keywords)
- Modified palatal plate
- Pierre Robin sequence
- Weight gain