Medizinische Universität Graz - Research portal
Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Hennen, D; Hartmann, D; Rieger, PH; Oesterreicher, A; Wiener, J; Arbeiter, F; Feuchter, M; Frohlich, E; Pichelmayer, M; Schlogl, S; Griesser, T.
Exploiting the Carbon and Oxa Michael Addition Reaction for the Synthesis of Yne Monomers: Towards the Conversion of Acrylates to Biocompatible Building Blocks.
CHEMPHOTOCHEM. 2020;
Doi: 10.1002/cptc.201900199
Web of Science
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- Co-authors Med Uni Graz
- Fröhlich Eleonore
- Pichelmayer Margit
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- Abstract:
- Herein, we demonstrated the synthesis of multifunctional alkyne building blocks from commercially available acrylate monomers exploiting the carbon and oxa Michael addition reaction. These compounds were obtained in decent yields and show similar or even higher photoreactivity than the initial acrylates. Importantly, selected thiol-yne formulations can be processed by stereolithography and significantly outperform the corresponding acrylate in terms of modulus and toughness. The high compatibility of such cured materials with osteosarcoma cells makes these photopolymers interesting for hard tissue engineering.
- Find related publications in this database (Keywords)
- alkyne monomers
- biocompatibility
- Michael addition
- photopolymerization
- stereolithography
- thiol-yne reactions