Medizinische Universität Graz - Research portal

Go directly to the nagivation.
Go directly to the content.

Navigation/Search

Selected Publication:

SHR Neuro Cancer Cardio Lipid Metab Microb

Haas, AM; Mayer, C; Haas, A; Wackernagel, W.
Effect of intravitreal C₃F₈ gas in patients with vitreomacular traction: A retrospective case series.
Spektrum Augenheilkd. 2018; 32(6):228-238 Doi: 10.1007/s00717-017-0382-5 [OPEN ACCESS]
Web of Science PubMed FullText FullText_MUG

Co-authors Med Uni Graz: Haas Anton; Mayer-Xanthaki Christoph Fidel; Wackernagel Werner
Altmetrics:
Dimensions Citations:
Plum Analytics:
Scite (citation analytics):
Abstract:: We aimed to assess the efficacy of a single intravitreal perfluoropropane (C₃F₈) gas injection for the treatment of vitreomacular traction with or without a macular hole. In this retrospective case series, seven eyes of six patients with symptomatic vitreomacular traction documented on optical coherence tomography, one with a macular hole additionally, received a single intravitreal C₃F₈ gas injection of up to 0.3 ml. The primary endpoint was vitreomacular traction release at 1 month after injection. Secondary endpoints included resolution of vitreomacular adhesion within 6 months, nonsurgical closure of macular holes, and change in central foveal thickness and best-corrected visual acuity. Overall, on optical coherence tomography, six of seven eyes (85.7%) had release of vitreomacular traction during the entire study duration: three within 1 month of injection and the other three within 6 months. Of the latter group, two of the three eyes showed a concurrent epiretinal membrane and one concurrent diabetic retino- and maculopathy. The patient with a macular hole had resolution of vitreomacular traction within 1 month but had to undergo vitrectomy because of nonclosure of the macular hole. Associated adverse events were macular edema with a consequent lamellar hole after injection in one patient, and another patient developed retinal detachment. Intravitreal C₃F₈gas injection is an inexpensive and promising minimally invasive option for the treatment of symptomatic and persistent vitreomacular traction with or without a macular hole. Further larger studies, especially comparing C₃F₈ gas injection with other treatment options, are needed.
Find related publications in this database (Keywords): Intravitreal gas; Perfluoropropane (C3F8); Pneumatic vitreolysis; Vitreomacular adhesion; Vitreomacular traction