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Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Biebl, A; Grillenberger, A; Schmitt, K.
Enema-induced severe hyperphosphatemia in children.
Eur J Pediatr. 2009; 168(1):111-112
Doi: 10.1007/s00431-008-0705-2
(- Case Report)
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- Leading authors Med Uni Graz
- Biebl Ariane
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- Abstract:
- We report the case of a 13-year-old boy with Costello syndrome and chronic constipation who received phosphate-containing Fleet-pediatric enemas at regular intervals. The day before admission he was given four enemas for severe constipation. Within 24 h the boy had developed severe hyperphosphatemia (phosphate 17.75 mmol/L), hypertonic dehydration (sodium 171 mmol/L) and severe hypocalcemia (calcium 0.56 mmol/L). With early intervention and treatment, the child survived without sequelae. Osmotically acting hypertonic phosphate enemas may result in severe toxicity. Children with developmental delay often display bowel dysfunction and chronic constipation and are therefore high-risk patients. The accepted opinion-that these enemas are not absorbed and therefore systemically inactive-is not true. Physicians should be aware of the potentially lethal complications of this treatment, which is part of everyday clinical practice.
- Find related publications in this database (using NLM MeSH Indexing)
- Adolescent -
- Enema - adverse effects
- Humans -
- Hyperphosphatemia - diagnosis
- Hyperphosphatemia - drug therapy
- Hyperphosphatemia - etiology
- Hypertonic Solutions -
- Hypocalcemia - etiology
- Male -
- Severity of Illness Index -
- Find related publications in this database (Keywords)
- Chronic constipation
- Hyperphosphatemia
- Phosphate enemas