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Selected Publication:

Beitzke, A; Zobel, G; Zenz, W; Gamillscheg, A; Stein, JI.
Catheter-directed thrombolysis with recombinant tissue plasminogen activator for acute pulmonary embolism after fontan operation.
Pediatr Cardiol. 1996; 17(6):410-412 Doi: 10.1007%2Fs002469900091 (- Case Report)
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Leading authors Med Uni Graz
Beitzke Albrecht
Co-authors Med Uni Graz
Gamillscheg Andreas
Stein Joerg-Ingolf
Zenz Werner
Zobel Gerfried
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Abstract:
We report the case of a 3-year-old girl who presented with near-lethal pulmonary thrombembolism 3 weeks after an uneventful Fontan operation. Complete occlusion of the left lower lobe pulmonary artery had occurred together with a cerebral infarction. Recombinant tissue plasminogen activator (rt-Pa) was used for thrombolysis because of its short half-life and its clot-selective properties. To further minimize the systemic effects of rt-PA, local catheter-directed lysis was performed. A prolonged course of low-dose rt-PA therapy achieved complete lysis without side effects.
Find related publications in this database (using NLM MeSH Indexing)
Catheterization -
Cerebral Infarction - etiology
Child, Preschool - etiology
Female - etiology
Fontan Procedure - etiology
Humans - etiology
Postoperative Complications - drug therapy
Pulmonary Embolism - drug therapy
Recombinant Proteins - therapeutic use
Thrombolytic Therapy - methods
Tissue Plasminogen Activator - therapeutic use

Find related publications in this database (Keywords)
Pulmonary Embolism
Fontan Operation
Thrombolysis
Tissue Plasminogen Activator
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