Medizinische Universität Graz - Research portal
Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Gergei, I; Krämer, BK; Scharnagl, H; Stojakovic, T; März, W; Mondorf, U.
Propeptide big-endothelin, N-terminal-pro brain natriuretic peptide and mortality. The Ludwigshafen risk and cardiovascular health (LURIC) study.
Biomarkers. 2016; 22(3-4):315-320
Doi: 10.1080/1354750X.2016.1252969
Web of Science
PubMed
FullText
FullText_MUG
- Co-authors Med Uni Graz
- März Winfried
- Scharnagl Hubert
- Stojakovic Tatjana
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- Abstract:
- The endothelin system (Big-ET-1) is a key regulator in cardiovascular (CV) disease and congestive heart failure (CHF). We have examined the incremental value of Big-ET-1 in predicting total and CV mortality next to the well-established CV risk marker N-Terminal Pro-B-Type Natriuretic Peptide (NT-proBNP). Big-ET-1 and NT-proBNP were determined in 2829 participants referred for coronary angiography (follow-up 9.9 years). Big-ET-1 is an independent predictor of total, CV mortality and death due to CHF. The conjunct use of Big-ET-1 and NT-proBNP improves the risk stratification of patients with intermediate to high risk of CV death and CHF. Big-ET-1improves risk stratification in patients referred for coronary angiography.
- Find related publications in this database (using NLM MeSH Indexing)
- Cardiovascular Diseases - blood
- Cardiovascular Diseases - diagnosis
- Cardiovascular Diseases - mortality
- Coronary Angiography -
- Endothelin-1 - blood
- Female -
- Follow-Up Studies -
- Heart Failure - blood
- Heart Failure - diagnosis
- Heart Failure - mortality
- Humans -
- Male -
- Middle Aged -
- Natriuretic Peptide, Brain - blood
- Peptide Fragments - blood
- Predictive Value of Tests -
- Risk Assessment -
- Find related publications in this database (Keywords)
- N-terminal-pro brain natriuretic peptide
- big endothelin-1
- congestive heart failure
- cardiovascular mortality
- biomarker