Medizinische Universität Graz - Research portal

Go directly to the nagivation.
Go directly to the content.

Navigation/Search

Selected Publication:

SHR Neuro Cancer Cardio Lipid Metab Microb

Massone, C; Fink-Puches, R; Cerroni, L.
Atypical clinical presentation of primary and secondary cutaneous follicle center lymphoma (FCL) on the head characterized by macular lesions.
J Am Acad Dermatol. 2016; 75(5):1000-1006 Doi: 10.1016/j.jaad.2016.05.039
Web of Science PubMed FullText FullText_MUG

Leading authors Med Uni Graz: Cerroni Lorenzo; Massone Cesare
Co-authors Med Uni Graz: Fink-Puches Regina
Altmetrics:
Dimensions Citations:
Plum Analytics:
Scite (citation analytics):
Abstract:: Primary cutaneous follicle center lymphoma (pcFCL) usually presents with reddish nodules, plaques, and tumors on the head and neck or the back. We sought to describe a peculiar clinical presentation of pcFCL and secondary cutaneous follicle center lymphoma (FCL). We report a series of 13 patients (7 male and 6 female; median age 58 years, mean age 58.2 years, age range 26-83 years) with either pcFCL (11 patients) or secondary cutaneous FCL (2 patients) presenting with lesions on the head deviating from the classic clinical manifestations characterized by plaques and tumors. All patients presented clinically with diffuse, ill-defined, partly hypochromic, partly erythematous macules or with inconspicuous lesions located predominantly on the scalp and forehead. Dimension ranged between 4 to 5 cm² and greater than 30 cm². The initial diagnosis was never cutaneous lymphoma, and all patients received various diagnoses including rosacea, alopecia, erysipelas, discoid lupus erythematosus, angiosarcoma, Borrelia infection, or sarcoidosis. Histologic examination confirmed the diagnosis of FCL in all patients. Small number of cases and retrospective study design are limitations. This clinical presentation of both pcFCL and secondary cutaneous FCL is unusual and represents a pitfall in the clinical diagnosis. Dermatologists should be aware of this clinical variant of FCL to establish a timely diagnosis and treat patients properly. Copyright © 2016 American Academy of Dermatology, Inc. Published by Elsevier Inc. All rights reserved.
Find related publications in this database (using NLM MeSH Indexing): Adult -; Aged -; Aged, 80 and over -; Biopsy -; Diagnostic Errors -; Erythema - diagnosis; Erythema - etiology; Erythema - pathology; Facial Neoplasms - diagnosis; Facial Neoplasms - pathology; Female -; Forehead - pathology; Germinal Center - pathology; Head and Neck Neoplasms - diagnosis; Head and Neck Neoplasms - pathology; Humans -; Lymphoma, Follicular - diagnosis; Lymphoma, Follicular - pathology; Male -; Middle Aged -; Retrospective Studies -; Scalp - pathology; Skin Diseases - diagnosis; Skin Neoplasms - diagnosis; Skin Neoplasms - pathology; Skin Neoplasms - secondary; Symptom Assessment -
Find related publications in this database (Keywords): alopecia; cutaneous B-cell lymphoma; diffuse macule; large cell lymphocytoma; primary cutaneous follicle center lymphoma; secondary cutaneous follicle center lymphoma