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Bruns, H; Krätschmer, K; Hinz, U; Brechtel, A; Keller, M; Büchler, MW; Schemmer, P.
Quality of life after curative liver resection: a single center analysis.
World J Gastroenterol. 2010; 16(19):2388-2395
Doi: 10.3748/wjg.v16.i19.2388
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- Leading authors Med Uni Graz
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Schemmer Peter
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- Abstract:
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To evaluate quality of life (QoL) after curative liver resection and identify variables associated with decreased QoL.
From October 2001 to July 2004, 323 patients underwent liver resection. At 3-36 mo after discharge, 188 patients were disease free. QoL was assessed using the Short Form (SF)-12 Health Survey with mental and physical component scales (SF-12 MCS and PCS), supplemented with generic questions concerning pain and liver-specific items.
Sixty-eight percent (128/188) returned the questionnaire, which was completed in 75% (96/128) of cases. Median SF-12 PCS and MCS were 46.7 (interquartile range: 34.2-53.9) and 54.1 (42.8-58.2). Fifty percent were pain free with a median symptom score of 1.75 (1.38-2.13). PCS was higher after major hepatectomy [57% (55/96)] compared to minor resection (P = 0.0049), which represented an improved QoL. QoL was not affected by sex but by age compared to the general German population. MCS was higher after liver surgery for metastatic disease [55.9 (47.5-58.8)] compared to primary carcinoma [49.6 (36.5-55.1)] and benign disease [49.2 (37.7-56.3)] (P = 0.0317). There was no correlation between length of postoperative period and QoL. Pain, deficiencies in everyday life and a high symptom score significantly decreased MCS and PCS.
Most patients were only marginally affected even after major liver resection; however, minor complications were associated with decreased SF-12 MCS and PCS and need careful attention.
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Adult -
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Aged -
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Disease-Free Survival -
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Female -
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Female -
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Hepatectomy - adverse effects
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Hepatectomy - psychology
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Humans -
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Male -
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Middle Aged -
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Pain Measurement -
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Pain, Postoperative - etiology
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Pain, Postoperative - psychology
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Prospective Studies -
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Quality of Life -
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Surveys and Questionnaires -
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Time Factors -
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Treatment Outcome -
- Find related publications in this database (Keywords)
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Quality of life
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Liver resection