Medizinische Universität Graz - Research portal
Selected Publication:
Tiran, B; Karpf, E; Tiran, A.
Age dependency of selenium and cadmium content in human liver, kidney, and thyroid.
ARCH ENVIRON HEALTH. 1995; 50(3): 242-246.
Doi: 10.1080/00039896.1995.9940394
Web of Science
PubMed
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FullText_MUG
- Leading authors Med Uni Graz
- Tiran Beate
- Co-authors Med Uni Graz
- Kampelmühler Eva
- Tiran Andreas
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- Abstract:
- Selenium and cadmium concentrations were investigated in 60 autopsy tissue samples obtained from fetal life up to adulthood (defined in this study as 25-87 y of age) in Styria, a moderately industrialized region in Austria that has a low selenium supply. During the first 2 y after birth, median liver selenium concentrations were slightly lower (i.e., 1.5 nmol/g wet weight) than concentrations found in fetal life (i.e., 2.9 nmol/g) and adulthood (2.1 nmol/g). Whereas in the fetal period median selenium content in the kidney cortex (2.1 nmol/g) and the thyroid gland (1.6 nmol/g) was lower than that found in the liver, the reverse was true for adults (i.e., kidney, 5.5 nmol/g; thyroid, 4.3 nmol/g). Tissue cadmium concentrations approached 0 during gestation. Accumulation in the kidney and liver commenced immediately after birth. In the thyroid gland of adults, significantly higher concentrations of cadmium were found. Median concentrations in adults showed no statistical significant age dependency (i.e., liver, 7.6 nmol/g; kidney, 59.8 nmol/g; thyroid, 11.2 nmol/g). In summary, the data revealed very low tissue selenium concentrations and low cadmium burdens for the Styrian population that was not exposed occupationally.
- Find related publications in this database (using NLM MeSH Indexing)
- Adolescent -
- Adult -
- Age Factors -
- Aged -
- Aged, 80 and over -
- Analysis of Variance -
- Austria -
- Autopsy -
- Cadmium - analysis
- Child - analysis
- Child, Preschool - analysis
- Female - analysis
- Fetus - chemistry
- Gestational Age - chemistry
- Humans - chemistry
- Infant - chemistry
- Infant, Newborn - chemistry
- Kidney - chemistry
- Liver - chemistry
- Male - chemistry
- Middle Aged - chemistry
- Selenium - analysis
- Spectrophotometry, Atomic - analysis
- Thyroid Gland - chemistry