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Radeleff, B; Schawo, S; Hoffmann, K; Schemmer, P; Noeldge, G; Kauffmann, GW; Froehlich, B; Richter, GM.
Efficacy and safety of percutaneous transhepatic portal embolization before right liver resection using an ethibloc/lipiodol mixture: a single-center experience.
Dig Surg. 2008; 25(1):52-59
Doi: 10.1159/000118795
Web of Science
PubMed
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- Co-authors Med Uni Graz
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Schemmer Peter
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- Abstract:
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The purpose of this study was to evaluate the safety and efficacy of percutaneous transhepatic portal vein embolization of the right portal vein with an Ethibloc/Lipiodol mixture to induce hypertrophy of the left liver lobe in patients with primarily unresectable liver tumor.
15 patients (8 primary liver tumors, 7 liver metastases) underwent portal vein embolization. Liver volumetry, duration of hospitalization, complication rates, relevant laboratory values were documented.
In 13/15 patients (84.6%) embolization could be performed with a median of 8.8 ml (range 1.5-28 ml) Ethibloc/Lipiodol. One minor procedure-related complication (subcapsular hematoma) occurred, which did not affect the two-step liver resection. No patient developed acute liver failure after embolization or liver resection. The volume of the left liver lobe increased significantly (p = 0.0015) by 25% from a median of 750 ml (587-1,114 ml) to 967 ml (597-1,249 ml). 11/13 (81.8%) of the embolized patients underwent liver resection at a median of 49 days after embolization. Median hospitalization time was 4 days after embolization and 7 days after liver resection. Median overall survival of the 11 operated patients was 376 days.
Percutaneous transhepatic portal vein embolization using an Ethibloc/Lipiodol mixture is a safe, feasible, and efficient interventional procedure.
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Adult -
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Aged -
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Diatrizoate - administration & dosage
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Drug Combinations -
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Embolization, Therapeutic -
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Fatty Acids - administration & dosage
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Female -
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Hepatectomy -
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Humans -
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Iodized Oil - administration & dosage
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Liver Regeneration -
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Male -
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Middle Aged -
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Portal Vein -
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Propylene Glycols - administration & dosage
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Prospective Studies -
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Sclerosing Solutions - administration & dosage
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Treatment Outcome -
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Zein - administration & dosage
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portal vein
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angiography
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embolization
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ethibloc
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liver resection
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liver metastases