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SHR Neuro Cancer Cardio Lipid Metab Microb

Benati, E; Ribero, S; Longo, C; Piana, S; Puig, S; Carrera, C; Cicero, F; Kittler, H; Deinlein, T; Zalaudek, I; Stolz, W; Scope, A; Pellacani, G; Moscarella, E; Piraccini, BM; Starace, M; Argenziano, G.
Clinical and dermoscopic clues to differentiate pigmented nail bands: an International Dermoscopy Society study.
J Eur Acad Dermatol Venereol. 2017; 31(4):732-736 Doi: 10.1111/jdv.13991
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Co-authors Med Uni Graz
Kränke Teresa Maria
Zalaudek Iris
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Abstract:
Longitudinal melanonychia might be difficult to differentiate and the use of dermoscopy can be useful for the preoperative evaluation and management decision. The aim of our study was to investigate clinical and dermoscopic criteria of acquired longitudinal melanonychia in adults to identify the best predictors of melanoma using a multivariate analysis and to explore eventual new dermoscopic criteria for nail melanoma diagnosis. In this retrospective observational study, 82 histopathologically diagnosed, acquired nail pigmented bands were collected and examined. All variables were included in the analysis and examined as possible predictors of nail melanoma. Both univariate and multivariable analyses have been performed. Among 82 cases, 25 were diagnosed as nail melanoma and 57 as benign lesions (including 32 melanocytic nevi and 25 benign melanocytic hyperplasia). Melanoma cases were significantly associated with a width of the pigmented band higher than 2/3 of the nail plate, grey and black colours, irregularly pigmented lines, Hutchinson and micro-Hutchinson signs, and nail dystrophy. Granular pigmentation, a newly defined dermoscopic criterion, was found in 40% of melanomas and only in 3.51% of benign lesions. Dermoscopic examination of longitudinal melanonychia provides useful information that could help clinicians to improve melanoma recognition. © 2016 European Academy of Dermatology and Venereology.
Find related publications in this database (using NLM MeSH Indexing)
Adolescent -
Adult -
Aged -
Dermoscopy -
Diagnosis, Differential -
Humans -
Hyperpigmentation - diagnostic imaging
Hyperpigmentation - etiology
Hyperplasia - complications
Hyperplasia - diagnostic imaging
Melanocytes - pathology
Melanoma - complications
Melanoma - diagnostic imaging
Middle Aged -
Nail Diseases - diagnostic imaging
Nail Diseases - pathology
Nevus, Pigmented - complications
Nevus, Pigmented - diagnostic imaging
Retrospective Studies -
Skin Neoplasms - complications
Skin Neoplasms - diagnostic imaging
Young Adult -

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