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Resch, B; Kurath-Koller, S; Eibisberger, M; Zenz, W.
Prematurity and the burden of influenza and respiratory syncytial virus disease.
World J Pediatr. 2016; 12(1):8-18 Doi: 10.1007/s12519-015-0055-x
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Leading authors Med Uni Graz
Resch Bernhard
Co-authors Med Uni Graz
Eibisberger Monika
Kurath-Koller Stefan
Zenz Werner
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Abstract:
Respiratory morbidity of former preterm infants and especially those with bronchopulmonary dysplasia (BPD) is high during infancy and early childhood. We performed a review based on a literature search including EMBASE, MEDLINE, and CINAHL databases to identify all relevant papers published in the English and German literature on influenza and respiratory syncytial virus infection associated with preterm infant, prematurity, and BPD between 1980 and 2014. Recurrent respiratory symptoms remain common at preschool age, school age and even into young adulthood. Acute viral respiratory tract infections due to different pathogens cause significant morbidity and necessitate rehospitalizations during the first years of life. Influenza virus infection plays a minor role compared to respiratory syncytial virus (RSV) associated respiratory tract infection during infancy and early childhood. Nevertheless, particular morbidity to both viruses is high. The particular burden of both viral diseases in preterm infants is dominated by RSV and its associated rehospitalizations during the first two years of life. Prophylactic measures include vaccination against influenza virus of family members and caregivers and active immunization starting at the age of 6 months, and monthly injections of palivizumab during the cold season to avoid severe RSV disease and its sequelae.
Find related publications in this database (using NLM MeSH Indexing)
Bronchopulmonary Dysplasia - complications
Humans -
Infant, Newborn -
Infant, Premature -
Infant, Premature, Diseases - epidemiology
Influenza, Human - complications
Influenza, Human - epidemiology
Respiratory Syncytial Virus Infections - complications
Respiratory Syncytial Virus Infections - epidemiology
Respiratory Syncytial Virus Infections - therapy

Find related publications in this database (Keywords)
bronchopulmonary dysplasia
influenza
preterm infant
respiratory infectious disease
respiratory syncytial virus
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