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SHR Neuro Cancer Cardio Lipid Metab Microb

Münch, A; Langner, C.
Microscopic colitis: clinical and pathologic perspectives.
Clin Gastroenterol Hepatol. 2015; 13(2):228-236 Doi: 10.1016/j.cgh.2013.12.026
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Leading authors Med Uni Graz: Münch Andreas
Co-authors Med Uni Graz: Langner Cord
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Abstract:: Microscopic colitis is a chronic inflammatory bowel disease characterized by chronic nonbloody diarrhea and specific histopathology features. Active disease, defined as 3 or more stools or 1 or more watery stools per day, significantly reduces quality of life. Epidemiologic studies have found the incidence and prevalence of microscopic colitis to be comparable with those of Crohn's disease and ulcerative colitis. Nevertheless, microscopic colitis is still under-recognized in clinical practice-most health care workers know little about its etiology and pathophysiology. Furthermore, there are many challenges to the diagnosis and treatment of patients. We review the epidemiologic and clinical features of this disorder and discuss its pathogenesis. We also outline the criteria for histopathologic evaluation of microscopic colitis, recently published by the European Consensus on Inflammatory Bowel Disease, and discuss a treatment algorithm created by the European Microscopic Colitis Group. Treatment options for patients with budesonide-refractory disease are discussed. Copyright © 2015 AGA Institute. Published by Elsevier Inc. All rights reserved.
Find related publications in this database (using NLM MeSH Indexing): Anti-Inflammatory Agents - therapeutic use; Budesonide - therapeutic use; Colitis, Microscopic - diagnosis; Colitis, Microscopic - drug therapy; Colitis, Microscopic - epidemiology; Colitis, Microscopic - pathology; Humans -; Treatment Outcome -
Find related publications in this database (Keywords): Colon; EMCG; Immune Response; Therapy