Medizinische Universität Graz - Research portal
Selected Publication:
Wolf, G; Kohek, P; Geyer, E; Pakisch, B; Langsteger, W; Ramschak, S; Passath, A.
Intraoperative radiation therapy, endotracheal hyperthermia and IR-192-brachytherapy in patients with advanced thyroid cancer.
Acta Med Austriaca. 1996; 23(1-2):76-79
Web of Science
PubMed
- Leading authors Med Uni Graz
- Wolf Gerhard
- Co-authors Med Uni Graz
- Kohek Peter
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- Abstract:
- Tracheal stenosis due to infiltrative nonresectable thyroid cancer causes severe reduction in life quality. Palliative therapy, apart from tracheostomy is--up to now--intraluminal and/or external radiation. Good tumor control is achieved by local hyperthermia. A combined modality treatment (CMT) consisting of surgery, brachytherapy and intraoperative radiation, eventually combined with intraluminal NdYg-Laser-desobliteration was performed. An intraoperative radiation therapy (IORT)-protocol was designed for poorly differentiated non-anaplastic thyroid carcinoma. Out of 155 cases of differentiated thyroid tumors, 12 showed marked vascular and/or capsular invasion. Five entered the study (3 primarily local invasive tumors, 2 local recurring). IORT was administered after tumor surgery (4-10 Gy) and combined with postoperative percutaneous irradiation. The tumor control rate in the thyroid bed is 5/5, 1/5 developed mediastinal nodes, 1/5 with primary mediastinal tumor extend shows tumor progression. No specific complications occurred.
- Find related publications in this database (using NLM MeSH Indexing)
- Adenocarcinoma, Follicular - pathology
- Brachytherapy - instrumentation
- Carcinoma, Papillary - pathology
- Combined Modality Therapy - pathology
- Female - pathology
- Humans - pathology
- Hyperthermia, Induced - instrumentation
- Laser Surgery - instrumentation
- Lymph Node Excision - instrumentation
- Male - instrumentation
- Middle Aged - instrumentation
- Neoplasm Invasiveness - instrumentation
- Neoplasm Staging - instrumentation
- Palliative Care - instrumentation
- Radiotherapy Dosage - instrumentation
- Radiotherapy, Adjuvant - instrumentation
- Thyroid Gland - pathology
- Thyroid Neoplasms - pathology
- Tracheal Stenosis - pathology
- Find related publications in this database (Keywords)
- Thyroid Carcinoma
- Surgical Treatment
- Intraoperative Radiotherapy
- Laser Surgery
- Brachytherapy
- Endoluminal Irradation
- Hyperthermia
- Interdisciplinary Treatment