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SHR Neuro Cancer Cardio Lipid Metab Microb
Nagele, E; Jeitler, K; Horvath, K; Semlitsch, T; Posch, N; Herrmann, KH; Grouven, U; Hermanns, T; Hemkens, LG; Siebenhofer, A.
Clinical effectiveness of stress-reduction techniques in patients with hypertension: systematic review and meta-analysis.
J Hypertens. 2014; 32(10):1936-1944
Doi: 10.1097/HJH.0000000000000298
Web of Science
PubMed
FullText
FullText_MUG
- Leading authors Med Uni Graz
- Nagele Eva Helene
- Co-authors Med Uni Graz
- Horvath Karl
- Jeitler Klaus
- Semlitsch Thomas
- Siebenhofer-Kroitzsch Andrea
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- Abstract:
- A systematic review and meta-analysis focusing on patient-relevant outcomes and blood pressure was conducted to assess the clinical effectiveness of stress-reduction techniques in adults with essential hypertension. Systematic reviews and randomized controlled trials (RCTs) were identified as part of a systematic search in six electronic databases ending September 2012. RCTs comparing stress-reduction techniques versus no such techniques with a follow-up of at least 24 weeks and published in English or German were included. Outcomes of interest were death, cardiovascular morbidity/mortality, end-stage renal disease, health-related quality of life, adverse events, changes in blood pressure, and changes in antihypertensive medication. When appropriate, meta-analyses were used to combine data. Seventeen RCTs analyzing different stress-reduction techniques such as biofeedback, relaxation or combined interventions were identified. Data were not reported for most of the patient-relevant outcomes, and meta-analyses could only be used to evaluate effects on blood pressure. The data indicated a blood pressure-lowering effect, but the studies had methodological shortcomings and heterogeneity between them was high. Mean group differences for DBP ranged from -10 to 1 mmHg and for SBP from -12 to 10 mmHg. In terms of antihypertensive medication, no favorable effects of stress-reduction techniques could be identified. The available RCTs on stress-reduction techniques used for at least 24 weeks appeared to indicate a blood pressure-lowering effect in patients with essential hypertension, but this should be interpreted with caution because of major methodological limitations. A benefit of specific stress-reduction techniques in hypertensive patients remains unproven.
- Find related publications in this database (using NLM MeSH Indexing)
- Adult -
- Antihypertensive Agents - therapeutic use
- Blood Pressure - drug effects
- Essential Hypertension -
- Harm Reduction -
- Humans -
- Hypertension - complications
- Hypertension - drug therapy
- Hypertension - therapy
- Kidney Failure, Chronic - etiology
- Kidney Failure, Chronic - mortality
- Quality of Life -
- Stress, Psychological - therapy
- Treatment Outcome -
- Find related publications in this database (Keywords)
- hypertension
- relaxation therapy
- stress management
- stress-reduction techniques
- systematic review