Selected Publication:
Kamolz, LP; Andel, H; Greher, M; Ploner, M; Meissl, G; Frey, M.
Serum cholinesterase activity reflects morbidity in burned patients.
Burns. 2002; 28(2):147-150
Doi: 10.1016/S0305-4179(01)00091-2
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- Leading authors Med Uni Graz
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Kamolz Lars-Peter
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- Abstract:
- Blood samples of 200 patients with thermal injuries were drawn apparently to determine the trend of the cholinesterase activity. In relation to the severity of the injury, a characteristic decrease was noted during the first days after admission. A recovery to normal values was achieved in all survivors (150 patients) after a proportionate period of time, but in the group of non-survivors (50 patients), no complete recovery to normal levels was found. Furthermore, a significant relationship between serum cholinesterase activity and the severity of morbidity was detected, the fall of the cholinesterase activity at the very beginning was significantly higher (P<0.004) in patients who died (1.3kU/l) than in patients who survived (0.7kU/l). Already 24h after admission, the mean activity was significantly lower (P<0.003) in non-survivors (2.5kU/l) than in survivors (3.2kU/l). It seems that the serum cholinesterase is a sensitive indicator for the morbidity of patients with severe burn injuries.
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Analysis of Variance -
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Burns - enzymology Burns - mortality Burns - physiopathology
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Cholinesterases - blood
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Female -
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Humans -
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Male -
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Middle Aged -
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Severity of Illness Index -
- Find related publications in this database (Keywords)
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serum cholinesterase activity
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burned patients
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severity of illness