Medizinische Universität Graz - Research portal
Selected Publication:
Brezinschek, HP; Wilders-Truschnig, M; Leb, G; Eber, O; Dohr, G; Lanzer, G; Krejs, GJ.
Thyroid growth promoting serum-IgG in endemic goiter.
Acta Med Austriaca. 1990; 17 Suppl 1:26-27
Web of Science
PubMed
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- Leading authors Med Uni Graz
- Brezinsek Hans-Peter
- Co-authors Med Uni Graz
- Dohr Gottfried
- Krejs Günter Josef
- Lanzer Gerhard
- Leb Georg
- Truschnig-Wilders Martini
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- Abstract:
- In this study a strain of differentiated rat thyroid cells in continuous culture was used to detect the presence of thyroid growth promoting immunoglobulins (TGI) in IgG preparations of serum of patients with endemic and sporadic euthyroid goiters. TGI was detected when FRTL5 cells were used in a mitotic arrest assay by costimulating the cells with IgG and a suboptimal dose of TSH. TGI was present in 65 of 71 endemic goter cases and in 9 of 14 sporadic goiter cases.
- Find related publications in this database (using NLM MeSH Indexing)
- Autoantibodies - physiology
- Cell Division - physiology
- Culture Techniques -
- Goiter, Endemic - immunology
- Humans -
- Immunoglobulin G - physiology
- Immunoglobulins, Thyroid-Stimulating -