Medizinische Universität Graz Austria/Österreich - Forschungsportal - Medical University of Graz
Gewählte Publikation:
Stauber, RE; Horina, JH; Trauner, M; Krejs, GJ; Ratschek, M; Klimpfinger, M.
Glomerulonephritis as late manifestation of severe alpha 1-antitrypsin deficiency.
Clin Investig. 1994; 72(5):404-408
Doi: 10.1007/BF00252839
(- Case Report)
Web of Science
PubMed
FullText
FullText_MUG
Google Scholar
- Führende Autor*innen der Med Uni Graz
- Stauber Rudolf
- Co-Autor*innen der Med Uni Graz
- Horina Joerg
- Krejs Günter Josef
- Ratschek Manfred
- Trauner Michael
- Altmetrics:
- Dimensions Citations:
- Plum Analytics:
- Scite (citation analytics):
- Abstract:
- An association of alpha 1-antitrypsin deficiency with glomerulonephritis is rare and has so far been observed only in children or young adults. We report a 63-year-old man with severe alpha 1-antitrypsin deficiency associated with pulmonary emphysema, cirrhosis of the liver, and mesangioproliferative glomerulonephritis with nephrotic syndrome. Following initial presentation with nephropathy, further work-up revealed alpha 1-antitrypsin deficiency of proteinase inhibitor Z. In the absence of glomerular alpha 1-antitrypsin deposits the relationship between renal disease and alpha 1-antitrypsin deficiency remains unclear. alpha 1-Antitrypsin deficiency should be considered in adults with abnormal renal function and chronic liver disease.
- Find related publications in this database (using NLM MeSH Indexing)
- Fatal Outcome -
- Glomerulonephritis, IGA - etiology
- Humans -
- Liver Cirrhosis - etiology
- Lung Diseases, Obstructive - complications
- Male -
- Middle Aged -
- Phenotype -
- Pulmonary Emphysema - etiology
- Smoking - adverse effects
- alpha 1-Antitrypsin Deficiency -
- Find related publications in this database (Keywords)
- Alpha(1)-Antitrypsin Deficiency
- Glomerulonephritis
- Cirrhosis