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Selected Publication:
SHR Neuro Cancer Cardio Lipid Metab Microb
Ovcina, I; Knez, I; Curcic, P; Ozkan, S; Nagel, B; Sorantin, E; Puchinger, M; Tscheliessnigg, K.
Pulmonary valve replacement with mechanical prostheses in re-do Fallot patients.
Interact Cardiovasc Thorac Surg. 2011; 12(6):987-991
Doi: 10.1510/icvts.2010.252254
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- Leading authors Med Uni Graz
- Knez Igor
- Ovcina Ismar
- Co-authors Med Uni Graz
- Curcic Pero
- Nagel Bert Hermann Philipp
- Özkan Sezen
- Puchinger Markus
- Sorantin Erich
- Tscheliessnigg Karlheinz
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- Abstract:
- In this prospective clinical study, we have compared 17 patients with tetralogy of Fallot (TOF) who received mechanical valve substitutes and had concomitant additional right ventricular (RV) volume reduction plasty (aRVVRP, group 1) with seven patients who underwent solitary re-do pulmonary valve replacements (PVR, group 2). All patients were evaluated by magnetic resonance imaging (MRI) two months pre- and four to six months postoperatively for assessment of ventricular geometry. At a mean follow-up of 31.9 months, the RV ejection fraction improved from 39.1 to 48.3% in group 1 vs. from 40.1 to 49% in group 2 (P<0.001), and RV indexed end-diastolic volume decreased from 174.8 to 119.9 ml/m(2) (group 1) vs. from 142.4 to 99.6 ml/m(2) (group 2, P<0.001). Indexed RV myocardial mass decreased from 52.3 to 38.7 g/m(2) in group 1 vs. 46.9 to 39.1 g/m(2) in group 2 (P<0.001). Follow-up revealed no mortality and distinct improvements in RV geometry, recommending mechanical prostheses as suitable alternatives for PVR. Selection criteria for this solution should consider multiple previous reoperations and assured patient compliance in terms of current anticoagulant usage and self-testing. aRVVRP could serve as an adjunct in re-dos of TOF surgery indicated by RV outflow tract dysfunction due to akinetic fibrous areas.
- Find related publications in this database (using NLM MeSH Indexing)
- Adolescent -
- Adult -
- Analysis of Variance -
- Analysis of Variance -
- Cardiac Surgical Procedures - adverse effects
- Child -
- Child, Preschool -
- Female -
- Heart Valve Prosthesis -
- Heart Valve Prosthesis Implantation - instrumentation
- Humans -
- Infant -
- Infant, Newborn -
- Magnetic Resonance Imaging -
- Male -
- Patient Selection -
- Prospective Studies -
- Prosthesis Design -
- Pulmonary Valve - physiopathology
- Pulmonary Valve - surgery
- Pulmonary Valve Insufficiency - etiology
- Pulmonary Valve Insufficiency - physiopathology
- Pulmonary Valve Insufficiency - surgery
- Recovery of Function -
- Reoperation -
- Stroke Volume -
- Tetralogy of Fallot - physiopathology
- Tetralogy of Fallot - surgery
- Time Factors -
- Treatment Outcome -
- Ventricular Function, Right -
- Ventricular Remodeling -
- Young Adult -
- Find related publications in this database (Keywords)
- Congenital heart disease
- Right ventricular outflow tract reconstruction
- Pulmonary valve replacement
- Mechanical prosthesis
- Right ventricular volume reduction plasty
- Reoperation